General Information:
Exercise testing for mice can be carried out using either our 4 lane automated treadmill apparatus, swimming pool, or on a self governing exercise wheel. Endpoints to these studies can include: 1) willingness to exercise 2) survival 3) documentation of rhythm disturbances 4) ventricular function assessment and 5) oxygen consumption.
All exercise studies are conducted in a dedicated space which houses our treadmill apparatus, swimming pool, and oxymax machine. Mice are monitored continuously during all exercise regimens by trained personnel.
Exercise Services & Data Output: [ request form ]
Treadmill:
This service employs the use of a motorized, speed controlled modular treadmill system designed specifically for mice. The treadmill is equipped with an electric shock stimulus for motivation and an adjustable inclination angle. The treadmill can be used for both long and short-term exercise studies. A technician is provided to conduct the study and gather date OR you may request full training on the use of the treadmill and for future studies conduct exercise studies without a provided technician.
Swimming:
This service employs the use of a specifically dimensioned container that is filled with 35 degree water to a depth of 25cm. Mice swim in groups of 5-8 per swim. A light current is kept running to stimulate the desire to swim. The pool can be used for both stress and long term exercise studies. A technician is provided to conduct the study and gather data and watch the mice closely to prevent drowning OR you may request full training on the use of the swimming pool and for future studies conduct swims without a provided technician.
Tech Assisted Treadmill and Swimming:
Data provided at study end: Spreadsheet documenting total time of exercise, failure periods, speed, and incline.
Mandatory One-time Tech Assisted Training (if using equipment without a tech for future studies):
Facility Charge for Equipment Use without a Tech:
Organ Harvest after Exercise:
Staff:
Michael Courtois
Education:
B.S., Chemistry, Southeast MO State University, Cape Girardeau, MO
B.S., Psychology, Washington University, St. Louis, MO
M.A., Experimental Psychology, University of Missouri-Columbia
Title:
Research Assistant Professor of Medicine
Carla Weinheimer
Education:
B.S. Animal Science – University of Illinois
M.S. Biology – Washington University in St.Louis
Title:
Research Assistant Professor
Staff Director- Cardiovascular Mouse Phenotyping Core
Work History:
1985-Present Cardiology, Internal Medicine, Washington University School of Medicine
Relevant Work Experience:
>20 years of cardiovascular animal surgery
Carrie Gierasch
Education:
B.S. Animal Science – University of Missouri, Columbia
Title:
Senior Research Technician
Work History:
1998-Present Cardiology, Internal Medicine, Washington University School of Medicine
1997-1998 Department of Animal Science, Reproductive Physiology Laboratory, University of Missouri, Columbia
Relevant Work Experience:
Reproductive Physiology Laboratory- Swine
Surgery & AI
Mouse Husbandry
Northern, Southern, Western Blotting
Murine Surgery
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