PUBLICATIONS

Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP.
CD36 Deficiency Rescues Lipotoxic Cardiomyopathy.
Circ Res. 2007 Mar 15; [Epub ahead of print]
PMID: 17363697 [PubMed - as supplied by publisher]

Ma X, Liu Y, Tittiger M, Hennig A, Kovacs A, Popelka S, Wang B, Herati R, Bigg M, Ponder KP.
Improvements in Mucopolysaccharidosis I Mice After Adult Retroviral Vector-mediated Gene Therapy with Immunomodulation.
Mol Ther. 2007 Feb 20; [Epub ahead of print]
PMID: 17311010 [PubMed - as supplied by publisher]

Lau JM, Jin X, Ren J, Avery J, DeBosch BJ, Treskov I, Lupu TS, Kovacs A, Weinheimer C, Muslin AJ.
The 14-3-3tau phosphoserine-binding protein is required for cardiomyocyte survival.
Mol Cell Biol. 2007 Feb;27(4):1455-66. Epub 2006 Dec 4.
PMID: 17145769 [PubMed - indexed for MEDLINE]

DeBosch B, Sambandam N, Weinheimer C, Courtois M, Muslin AJ.
Akt2 regulates cardiac metabolism and cardiomyocyte survival.
J Biol Chem. 2006 Oct 27;281(43):32841-51. Epub 2006 Aug 31.
PMID: 16950770 [PubMed - indexed for MEDLINE]

DeBosch B, Treskov I, Lupu TS, Weinheimer C, Kovacs A, Courtois M, Muslin AJ.
Akt1 is required for physiological cardiac growth.
Circulation. 2006 May 2;113(17):2097-104. Epub 2006 Apr 24.
PMID: 16636172 [PubMed - indexed for MEDLINE]

Betsuyaku T, Nnebe NS, Sundset R, Patibandla S, Krueger CM, Yamada KA.
Overexpression of cardiac connexin45 increases susceptibility to ventricular tachyarrhythmias in vivo.
Am J Physiol Heart Circ Physiol. 2006 Jan;290(1):H163-71. Epub 2005 Aug 26.
PMID: 16126808 [PubMed - indexed for MEDLINE]

Holland MR, Kovacs A, Posdamer SH, Wallace KD, Miller JG.
Anisotropy of apparent backscatter in the short-axis view of mouse hearts.
Ultrasound Med Biol. 2005 Dec;31(12):1623-9.
PMID: 16344125 [PubMed - indexed for MEDLINE]

Guo W, Jung WE, Marionneau C, Aimond F, Xu H, Yamada KA, Schwarz TL, Demolombe S, Nerbonne JM.
Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction.
Circ Res. 2005 Dec 9;97(12):1342-50. Epub 2005 Nov 17.
PMID: 16293790 [PubMed - indexed for MEDLINE]

Lou JY, Laezza F, Gerber BR, Xiao M, Yamada KA, Hartmann H, Craig AM, Nerbonne JM, Ornitz DM.
Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels.
J Physiol. 2005 Nov 15;569(Pt 1):179-93. Epub 2005 Sep 15.
PMID: 16166153 [PubMed - indexed for MEDLINE]

Gard JJ, Yamada K, Green KG, Eloff BC, Rosenbaum DS, Wang X, Robbins J, Schuessler RB, Yamada KA, Saffitz JE.
Remodeling of gap junctions and slow conduction in a mouse model of desmin-related cardiomyopathy.
Cardiovasc Res. 2005 Aug 15;67(3):539-47.
PMID: 15913582 [PubMed - indexed for MEDLINE]

Ren J, Zhang S, Kovacs A, Wang Y, Muslin AJ.
Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction.
J Mol Cell Cardiol. 2005 Apr;38(4):617-23.
PMID: 15808838 [PubMed - indexed for MEDLINE]

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP.
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
PLoS Biol. 2005 Apr;3(4):e101. Epub 2005 Mar 15.
PMID: 15760270 [PubMed - indexed for MEDLINE]

Chiu HC, Kovacs A, Blanton RM, Han X, Courtois M, Weinheimer CJ, Yamada KA, Brunet S, Xu H, Nerbonne JM, Welch MJ, Fettig NM, Sharp TL, Sambandam N, Olson KM, Ory DS, Schaffer JE.
Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy.
Circ Res. 2005 Feb 4;96(2):225-33. Epub 2004 Dec 23.
PMID: 15618539 [PubMed - indexed for MEDLINE]

Liu Y, Xu L, Hennig AK, Kovacs A, Fu A, Chung S, Lee D, Wang B, Herati RS, Mosinger Ogilvie J, Cai SR, Parker Ponder K.
Liver-directed neonatal gene therapy prevents cardiac, bone, ear, and eye disease in mucopolysaccharidosis I mice.
Mol Ther. 2005 Jan;11(1):35-47.
PMID: 15585404 [PubMed - indexed for MEDLINE]

Brunet S, Aimond F, Li H, Guo W, Eldstrom J, Fedida D, Yamada KA, Nerbonne JM.
Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles.
J Physiol. 2004 Aug 15;559(Pt 1):103-20. Epub 2004 Jun 11. Erratum in: J Physiol. 2004 Sep 15;559(Pt 3):985.
PMID: 15194740 [PubMed - indexed for MEDLINE]

Harris IS, Zhang S, Treskov I, Kovacs A, Weinheimer C, Muslin AJ.
Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload.
Circulation. 2004 Aug 10;110(6):718-23. Epub 2004 Aug 2.
PMID: 15289381 [PubMed - indexed for MEDLINE]

Kovacs A, Courtois MR, Weinheimer CJ, Posdamer SH, Wallace KD, Holland MR, Miller JG.
Ultrasonic tissue characterization of the mouse myocardium: successful in vivo cyclic variation measurements.
J Am Soc Echocardiogr. 2004 Aug;17(8):883-92.
PMID: 15282494 [PubMed - indexed for MEDLINE]

Betsuyaku T, Kanno S, Lerner DL, Schuessler RB, Saffitz JE, Yamada KA.
Spontaneous and inducible ventricular arrhythmias after myocardial infarction in mice.
Cardiovasc Pathol. 2004 May-Jun;13(3):156-64.
PMID: 15081472 [PubMed - indexed for MEDLINE]

Petrich BG, Eloff BC, Lerner DL, Kovacs A, Saffitz JE, Rosenbaum DS, Wang Y.
Targeted activation of c-Jun N-terminal kinase in vivo induces restrictive cardiomyopathy and conduction defects.
J Biol Chem. 2004 Apr 9;279(15):15330-8. Epub 2004 Jan 23.
PMID: 14742426 [PubMed - indexed for MEDLINE]

Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE, Medeiros DM, Valencik ML, McDonald JA, Kelly DP.
Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.
Circ Res. 2004 Mar 5;94(4):525-33. Epub 2004 Jan 15.
PMID: 14726475 [PubMed - indexed for MEDLINE]

Schuster DP, Kovacs A, Garbow J, Piwnica-Worms D.
Recent advances in imaging the lungs of intact small animals.
Am J Respir Cell Mol Biol. 2004 Feb;30(2):129-38. Review.
PMID: 14729505 [PubMed - indexed for MEDLINE]

Li H, Guo W, Yamada KA, Nerbonne JM.
Selective elimination of I(K,slow1) in mouse ventricular myocytes expressing a dominant negative Kv1.5alpha subunit.
Am J Physiol Heart Circ Physiol. 2004 Jan;286(1):H319-28. Epub 2003 Oct 2.
PMID: 14527939 [PubMed - indexed for MEDLINE]

Faury G, Pezet M, Knutsen RH, Boyle WA, Heximer SP, McLean SE, Minkes RK, Blumer KJ, Kovacs A, Kelly DP, Li DY, Starcher B, Mecham RP.
Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency.
J Clin Invest. 2003 Nov;112(9):1419-28.
PMID: 14597767 [PubMed - indexed for MEDLINE]

Zhang S, Weinheimer C, Courtois M, Kovacs A, Zhang CE, Cheng AM, Wang Y, Muslin AJ.
The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis.
J Clin Invest. 2003 Mar;111(6):833-41.
PMID: 12639989 [PubMed - indexed for MEDLINE]

Kanno S, Kovacs A, Yamada KA, Saffitz JE.
Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice.
J Am Coll Cardiol. 2003 Feb 19;41(4):681-6.
PMID: 12598083 [PubMed - indexed for MEDLINE]

Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP.
A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.
Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1226-31. Epub 2003 Jan 27.
PMID: 12552126 [PubMed - indexed for MEDLINE]

Vega RB, Rothermel BA, Weinheimer CJ, Kovacs A, Naseem RH, Bassel-Duby R, Williams RS, Olson EN.
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy.
Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):669-74. Epub 2003 Jan 6.
PMID: 12515860 [PubMed - indexed for MEDLINE]

Lewis JS, Herrero P, Sharp TL, Engelbach JA, Fujibayashi Y, Laforest R, Kovacs A, Gropler RJ, Welch MJ.
Delineation of hypoxia in canine myocardium using PET and copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone).
J Nucl Med. 2002 Nov;43(11):1557-69.
PMID: 12411560 [PubMed - indexed for MEDLINE]

Betsuyaku T, Kovacs A, Saffitz JE, Yamada KA.
Cardiac structure and function in young and senescent mice heterozygous for a connexin43 null mutation.
J Mol Cell Cardiol. 2002 Feb;34(2):175-84.
PMID: 11851357 [PubMed - indexed for MEDLINE]

Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP.
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.
J Clin Invest. 2002 Jan;109(1):121-30.
PMID: 11781357 [PubMed - indexed for MEDLINE]

Kanno S, Lerner DL, Schuessler RB, Betsuyaku T, Yamada KA, Saffitz JE, Kovacs A.
Echocardiographic evaluation of ventricular remodeling in a mouse model of myocardial infarction.
J Am Soc Echocardiogr. 2002 Jun;15(6):601-9.
PMID: 12050601 [PubMed - indexed for MEDLINE]

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Center for Cardiovascular Research
Washington University School of Medicine