Ambulatory ECG, blood pressure, activity, temperature, and blood glucose measurements can be monitored through the use of a telemetry system developed by Data Sciences International. This system eliminates the need for tethering and allows us to monitor mice for cardiac rhythm disturbances or blood pressure in the conscious mouse over long periods of time.
Monitoring is done with different types of implants and cannot be done simultaneously. Highly specialized Ponemah software is used for monitoring each of these parameters and allows us to tailor the schedule of recordings to each investigator’s needs.
With space dedicated to housing mice undergoing telemetry services, our monitoring capabilities also allow us to:
- Collect data points continuously
- Collect data points on a schedule (e.g. 10 sec per hr; or 5 min every 3 hr)
- Record body temperature and activity
ECG, blood pressure, and blood glucose implant surgeries are performed under sterile conditions. After the surgery, mice are placed in a recovery area on a warmer for a period of up to one week. The scheduled recordings start 7-10 days post-surgery. Data are delivered to investigators for further analysis and we are available for consultation on all data issues.
Service and data output details
For ECG monitoring, the implant is placed sub-Q in the back and leads are placed in proper vectors.
This procedure includes implantation of transmitters, post-operative single ECG recording for 24 hours and transmitter removal. Additional recording time is available. Heart rates/representative rhythm strips are provided at study end. Services do not include identification or analysis of arrhythmias. Training in data interrogation can be purchased separately as a software package from DSI International.
Data provided at study end: Summary report including surgery, survival, implant information and recording dates; spreadsheets of scheduled sampling times, heart rates and averages; printouts of representative ECG traces; and files of complete data sets upon request.
Extra Services Available with ECG Telemetry:
- Additional recording sessions
- Pharmacological injections during study; prices vary
- Organ harvest
This procedure includes implantation of transmitters and carotid artery catheterization with a polyurethane ticking. Post-operative carotid pressure recordings for a single 24 hr recording session and eventual transmitter removal are included. Blood pressure fluctuations are recorded and data is collected and categorized. Blood pressure wave forms are provided at study end.
- Cost includes refurbishment of blood pressure catheter. Cost reflects directly the amount we are charged for refurbs and may, therefore, be increased without advanced notice if the amount charged by Data Sciences increases.
Data provided at study end: Summary report including surgery, survival, implant information and recording dates; spreadsheets of scheduled sampling times, mean pressures, systolic and diastolic pressures, pulse pressures, heart rates and averages; printouts of representative blood pressure traces; and files of complete data sets upon request.
Extra Services Available with BP Telemetry (additional charges apply):
- Additional recording sessions
- Pharmacological injections during study; prices vary
- Organ harvest